毒害艾美尔球虫感染对雏鸡肠组织热休克蛋白-70表达的影响

doi:10.11843/j.issn.0366-6964.2014.06.020

Abstract

Abstract:

Ninety chickens were divided into E.necatrix one time infection group, E.necatrix twice infection group,and control group.We researched dynamic change of HSP-70 expression in intestinal tissue of chickens infected with E.necatrix applying immunohistochemical method.The results showed that the HSP-70 expression in intestinal tissue of twice infection chickens were lower than the control chickens by different degrees at the 5th to 9th days after primer infection,the HSP-70 expression of duodenum,jejunum and caecum were significant or very significant lower than control chickens (P<0.05 or P<0.01),later rising rapidly,higher than control chickens at the 14th day and reached the peak；the HSP-70 expression in duodenum and jejunum of chickens showing a trend of significantly lower than control chickens at first,then gradually rising and higher than control chickens after the second challenge infection.But,the HSP-70 expression in intestinal tissue of E.necatrix one time infection chickens was higher than control chickens at the 6th,10th,15th day.These indicate that the primer infection have a certain degree of inhibition of HSP-70 expression in intestinal tissue of chickens,and the increase of HSP-70 expression is closely related with the degree of damage on the body with E.necatrix infection.This study provides important reference for the further study of pathogenic mechanism of coccidian.

CLC Number:

S855.9

ZHAI Jie，LYU Zhi-hui，MA Chun-xia，GAO Xue-li，LIU Chao-nan，WANG Quan-jie，LYU Xiao-ping，ZHENG Shi-min. Effect of Infection of E.necatrix on Heat Shock Protein (HSP)-70 Expression in Intestinal Tissue of Broiler Chickens[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2014, 45(6): 1004-1010.

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Effect of Infection of E.necatrix on Heat Shock Protein (HSP)-70 Expression in Intestinal Tissue of Broiler Chickens

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